Year: 2026 | Month: October-December | Volume: 11 | Issue: 4 | Pages: 22-36
DOI: https://doi.org/10.52403/gijhsr.20260403
Development and Analytical Evaluation of Salasaradi Gaṇa Bhavita Silajatu; A Classical Herbo-Mineral Formulation for Madhumeha
Dr. Mahaveer Singh Ashiya1, Dr. Manoj Barupal1, Prof. (Dr.) Govind Sahay Shukla2, Dr. Rajaram Agarwal3, Dr. Chandrabhn Sharma4, Dr. Sangeeta Indoria5, Dr. Manisha Goyal6, Dr. Ravi Pratap Singh7
1MD Scholar, 1MD Scholar, 2Vice Chancellor, 3HOD & Professor, 4Associate Professor, 5Assistant Professor, 6Associate Professor, 7Assistant Professor;
P.G. Department of Rasa Shastra and Bhaishajya Kalpana,
PGIA Dr. Sarvepalli Radhakrishnan Rajasthan Ayurved University, Jodhpur, Rajasthan, India
Corresponding Author: Dr. Mahaveer Singh Ashiya, Dr. Manoj Barupal
ABSTRACT
Background: Ayurvedic pharmaceutics comprises systematic procedures for the conversion of raw medicinal materials into therapeutically suitable dosage forms. The present pharmaceutical study was undertaken to evaluate the preparation of Salasaradi Gaṇa Bhavita Silajatu through sequential Sodhana, Bhavana, drying, powdering, and encapsulation procedures.
Materials and Methods: Raw Silajatu was subjected to Sodhana by the Agnitapi method using Triphala Kwatha. Half of the purified Silajatu was subjected to 21 Bhavana with Salasaradi Gaṇa Dravya Kwatha using an End Runner, while the remaining half was subjected to 21 Bhavana with the same Kwatha using a Wet Grinder. The Salasaradi Gaṇa Kwatha was prepared using 19 drugs out of the 23 drugs of the Salasaradi Gaṇa, taking 15 g of each drug in Yavakuta form. After completion of Bhavana, the material was dried, powdered, and filled into hard gelatin capsules of 500 mg strength.
Results: During preliminary Silajatu Sodhana, 1 kg of impure Silajatu yielded 450 g of purified Silajatu, corresponding to a 45% yield. In subsequent processing, 2 kg of impure Silajatu yielded 800 g of purified material in each of two Process, corresponding to a 40% yield. A total of 1900 g of Sodhita Silajatu was divided into two equal portions and subjected separately to 21 Bhavanas with Salasaradi Gaṇa Dravya Kwatha using an End Runner and Wet Grinder. The final weights obtained were 930 g from the End Runner (2.1% loss) and 920 g from the Wet Grinder (3.15% loss). A higher requirement of Kwatha was observed in the Wet Grinder. After drying and powdering, 3600 capsules of 500 mg were prepared.
Conclusion: The formulation was successfully prepared through a sequential pharmaceutical process involving Sodhana, Bhavana, drying, powdering, and encapsulation. The documented weight variation, yield, Kwatha requirement, processing time, and handling characteristics provide useful pharmaceutical parameters for reproducibility of Salasaradi Gaṇa Bhavita Silajatu.
Keywords: Salasaradi Gaṇa, Silajatu, Bhavana, Triphala Kwatha, Madhumeha, Ayurvedic Pharmaceutics.