Original Research Article
Year: 2019 | Month: April-June | Volume: 4 | Issue: 2 | Pages: 113-119
Effect of Brisk Walking on MDA and Blood Thiol levels in Healthy Volunteers
Samrta Gupta1, Swaranjeet Soni 2
1Associate Professor, 2Professor
Department of Biochemistry, Maharaja Agrasen Medical College, Agroha, Haryana, India.
Corresponding Author: Samrta Gupta
ABSTRACT
Brisk walking is a physical exercise where a person walks quickly. This form of aerobic activity uplifts mood, make physically fit, and improve the quality of life. A study was designed to assess the effect of brisk walking on plasma MDA levels and blood thiol levels in healthy volunteers (n=100) and was compared with a group of normal healthy controls (n=100). The experimental group was further subdivided into two groups, i.e. as group A (in the age group of 20-35 years) and group B (age 36-50 years) with equal participants in each group. Blood samples were taken before starting the brisk walking (baseline) and after 40 and 90 days. Plasma malonyldialdehyde (MDA) level was found to be significantly reduced (p <0.001) and blood thiol level was raised significantly (p< 0.001) after 40 days. Similarly, the changes in the both parameters were highly significant even after 90 days. Reduction in oxidative stress suggests that aerobic exercises are beneficial for maintaining good healthy.
Key words: MDA, Blood Thiol, Brisk walking, Lipid Peroxidation, Oxidative Stress.