Original Research Article
Year: 2019 | Month: October-December | Volume: 4 | Issue: 4 | Pages: 39-43
Prevalence of Nephropathy in Presymptomatic Phase of Undiagnosed Type-2 Diabetes Mellitus
Dr Tilak Ram1, Dr S. Siva Leela2, Dr Katragadda Prasanthi2, Dr Devishetty Manasa2, DR Prerana Suresh Hittalmani2, Dr Kopula Sivasaicharan2
1Associate Professor, 2Postgraduate Resident,
General Medicine, Mediciti Institute of Medical Sciences, Ghanpur, Medchal-501401.
Corresponding Author: Dr Tilak Ram
ABSTRACT
Background: This study was conducted to find out nephropathy in asymptomatic and previously undiagnosed patients of type 2 diabetes mellitus.
Method: A cross sectional descriptive study comprising of 300 subjects was carried out over a period of 3 year at our institute. Blood samples for fasting, postprandial blood sugar and renal function were collected; urine analysis for proteinuria; and HbA1c and body mass index estimated were carried out. All the subjects were evaluated for other confounding factors like smoking and hypertension.
Results: Diabetic nephropathy was detected in 75 out of 300 newly diagnosed DM patients. Macroalbuminuria and microalbuminuria was seen in 66 and 9 patients respectively. Forty one (24.1%) out of total 165 male patients; and 34 (25.1%) out of total 135 female patients had nephropathy. In our study diabetic nephropathy had statistically significant association with both HbA1c (p-0.001) and hypertension (p-0.001). BMI had no significant association with nephropathy (p-0.625).
Conclusion: This study shows significantly high prevalence of diabetic nephropathy among undiagnosed asymptomatic diabetic patients. The findings highlight the requirement for regular health evaluation and laboratory workup especially to look for asymptomatic hyperglycemiato detect and treat DM in early stage and prevent complications.
Key words: Nephropathy, Undiagnosed, Presymptomatic, Diabetes Mellitus (DM), Microvascular Complications,