Case Report
Year: 2020 | Month: April-June | Volume: 5 | Issue: 2 | Pages: 115-120
Embryological and Genetical Interpretations of Bilateral Polycystic Kidney Disease in a Neonate - A Case Report
Sathyanarayana N1, Aswinprakash S1, Sunitha P1, Arulmoli R1, Jagadeesh D1, Jai Ganesh K1, Sobana R1, Srilahari N2, Satyavathi Devi P3
1Faculty of Medicine, AIMST University, Semeling, Bedong, Malaysia.
2Faculty of Biomedical Engineering, National University of Singapore, Singapore.
3Department of Anatomy Prathima Institute of Medical Sciences, Karimnagar, Telangana, India.
Corresponding Author: Sathyanarayana N
ABSTRACT
Polycystic kidney disease is a rare developmental anomaly. It is inherited autosomal dominant or autosomal recessive. Autosomal recessive polycystic kidney disease (ARPKD), previously named infantile polycystic kidney disease. Clusters of cysts develop within the kidneys and fluid filled cysts displace normal renal tubules in this disease. This is characterized by cystic dilatation of the collecting ducts and progress to renal failure. We reported a case of Autosomal recessive polycystic kidney disease (ARPKD). Earlier antenatal ultrasonography had already detected the occurrence of polycystic kidney in fetus a day before delivery and it is confirmed after the parturition by fetal autopsy. The detailed study about the congenital anomalies of kidneys are significant for medical geneticists, embryologists, anatomists, pathologists, gynecologists, clinicians, urologists, transplant surgeons and radiologists.
Keywords: Autosomal recessive polycystic kidney disease (ARPKD), Autosomal dominant polycystic kidney disease (ADPKD), Congenital Anomalies, Autopsy.