Original Research Article
Year: 2022 | Month: January-March | Volume: 7 | Issue: 1 | Pages: 46-50
DOI: https://doi.org/10.52403/gijhsr.20220107
Role of Electrolytes in Cardiovascular Disease (CVD) among Dhule Population
Nilma Patil. V1, Ilanchezhian. T2, Mahale Aarti. Y3
1Assosiate Professor in Biochemistry, JMF’s ACPM Medical College and Hospital, Dhule, Maharashtra, India.
2Assistant Professor in Biochemistry, JMF’s ACPM Medical College and Hospital, Dhule, Maharashtra, India.
3Professor and HOD in Biochemistry, JMF’s ACPM Medical College and Hospital, Dhule, Maharashtra, India.
Corresponding Author: Ilanchezhian. T
ABSTRACT
Cardiovascular Disease (CVD) is one of the leading causes of morbidity and mortality across the world. World Health Organization (WHO) has declared cardiovascular disease as a modern epidemic. The common electrolyte abnormalities are hyponatremia, hypokalemia and in calcium ion. Several mechanisms interact to produce these alterations. The decrease in cardiac output leads directly to a reduction in renal blood flow, with impairment of renal excretion of water and electrolytes, and it causes the activation of several neurohormonal responses which affect both cardiovascular homeostasis and electrolyte balance. Electrolytes were measured with a benchtop AA (Modular ISE 900-Modul, Roche Diagnostics, Mannheim, Germany. Electrolytes instrument works on the principle of ion-selective electrodes (ISEs).
The main aim of the study was to find the electrolytes level alternations in the cardiovascular disease. We observed that cardiovascular diseases patients having at high risk for electrolytes depletion. Patients with heart failure may exhibit hyponatremia due to a decrease in water excretion, which may be related to the enhanced release of both angiotensin and vasopressin and can be exaggerated by diuretic therapy. Along with potassium and calcium that influences cardiovascular function. The two most important electrolytes are potassium and calcium. They are both vitally concerned with proper function of the cardiac muscle. Both electrolytes are needed in the proper amounts for contraction of the muscle and for the proper conduction of heart impulses through the special conduction pathway in the heart. Therefore, these findings should warrant the clinician to address for the recovery from CVD.
Keywords: Cardiovascular disease (CVD), Hyponatremia, Hypokalemia, Ionized Calcium, Diuretics.