Original Research Article
Year: 2019 | Month: July-September | Volume: 4 | Issue: 3 | Pages: 47-50
Study of Serum Lipid Profile and Uric Acid Levels in Preeclampsia
Dr. Lata Bishnoi1, Dr. R K Vyas2, Dr. Yogita Soni3, Dr. Meenakshi Gora4
1Asst. Professor, 2Sr. Professor, 3Professor, 4Asst. Professor
Department of Biochemistry, S.P. Medical College, Bikaner, Rajasthan, India.
Corresponding Author: Dr. Lata Bishnoi
ABSTRACT
Introduction: Pre-eclampsia is common medical complications of pregnancy. Pregnancy is a physiological state associated with many alterations in metabolic, biochemical, physiological, haematological and immunological processes. Women with preeclampsia have a significant difference in lipid parameters and uric acid compared to normal pregnancy. Materials and Methods: The present study was conducted on 50 normal pregnant women (Group-I), 50 Pre-eclamptic pregnant women (Group-II). The blood samples collected from all the women and analyzed for serum lipid profile and uric acid. Results: Mean serum uric acid and triglyceride levels (p<0.001 and p<0.05 respectively) were significantly higher in pre-eclamptic group compared to control group. Total cholesterol and LDL-C was increased and HDL-C was decreased in pre-eclampsia group as compared to normal pregnant group but the results were not statistically significant. Conclusion: The assessment of serum lipids and uric acid are very useful markers to identify the occurrence of the complications of pre-eclampsia, which may reduce the risk of occurrence of disease.
Key words: Preeclampsia, Normal pregnancy, Dyslipidemia, lipid profile, uric acid.