Original Research Article
Year: 2021 | Month: October-December | Volume: 6 | Issue: 4 | Pages: 54-59
DOI: https://doi.org/10.52403/gijhsr.20211008
An Etiological and Clinical Study of Hepatomegaly among Patients of Region around Lucknow, UP
Padam Singh
Assistant Professor, Department of Medicine, Prasad Institute of Medical Sciences, Sarai Shahzaidi, Banthra, Lucknow, UP, India
ABSTRACT
Objective: To study the etiological and clinical spectrum of hepatomegaly among patients of the region around Lucknow.
Methods: This was a hospital based observational study conducted in the Department of Medicine, Prasad Institute of Medical Sciences, Lucknow. Patients of age 16-65 years were included in the study. Each patient of the study population had been subjected to detailed history that included symptomatology, history of alcohol consumption, drug history, high risk behavior etc.
Results: About one third of patients were between 21-30 years of age (31.3%). The most common cause of hepatomegaly was acute viral hepatitis (37.5%). Pain in abdomen was the most common clinical manifestation (89.1%) among hepatomegaly patients. The histopathological finding indicated that reticulum frame work was affected among 26.6% patients. Amoebic liver abscess cause of hepatomegaly was among males. Amoebic hepatitis cause of hepatomegaly was higher among females (75%) than males (25%). However, acute viral hepatitis cause of hepatomegaly was observed to be higher among males (79.2%) compared to females (20.8%).
Conclusion: Hepatomegaly varies from comparatively benign condition like fatty liver to fatal condition like hepatocellular carcinoma. The most common cause of hepatomegaly was acute viral hepatitis and most common presentation was pain in abdomen.
Multicenter study with large sample size is warranted to develop more insights about diagnosis and management of hepatomegaly.
Keywords: Hepatomegaly, Etiological, Histopathological.